8,411 research outputs found

    Colour Confinement and Deformed Baryons in Quantum Chromodynamics

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    The confinement of coloured entities in Quantum Chromodynamics (QCD) is traced to colour singletness of the observed entities. This is believed to arise from colour singlet state of quark-antiquark for mesons and a fully colour antisymmetric state for baryons. This demands a spherically symmetric baryon in the ground state. However it is pointed out that a deformed baryon in the ground state has been found to be extremely successful phenomenology. There are convincing experimental supports for a deformed nucleon as well. This means that something has been missed in the fundamental theory. In this paper this problem is traced to a new colour singlet state for baryons which has been missed hitherto and incorporation of which provides a consistent justification of a deformed baryon in the ground state. Interestingly this new colour singlet state is global in nature.Comment: 5 pages, 1 figur

    Synthesis, Characterization and Antibacterial Studies of Some New 1, 4-bis (3-Phenyl-4,5-Dihydroisoxazol-5-yl)Benzene Derivatives

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    Chalcones, analogs of 1,3-diarylprop-2-en-1-one, form a wide class of compounds containing two aromatic rings bound with vinyl ketone fragment. They are useful in synthesis of various heterocyclic compounds.Chalcones of plant origin are known [1]. Chalcones present great interest as compounds exhibiting antimalarial [2], antibacterial [3],  antifibrogenic [4], anticancer [5], antitrichomonal [6], anti-inflammatory [7],  antileishmanial [8], cytotoxic and antitrypanosoma cruzi [9] activities. While the flavonoid compounds are a group of natural products found in fruits, vegetables, nuts, seeds and flowers as well as in teas and are important constituent of human diet.  They have been demonstrated to possess antioxdidant [10], antihypertensive [11], antiallergic [12],  antinocicepative [13], trypsin inhibitors [14], plant growth regulator [15], antibacterial and antifungal [16,17] activities. In the last few years microwave induced organic reaction enhancement (MORE)  chemistry has gained popularity as a nonconventional technique for rapid organic synthesis [18] and many researchers have described accelerated organic reactions, and a large number of papers has appeared. Proving the synthetic utility of SMORE chemistry in routine organic synthesis [19] . It has been termed as ‘e-chemistry’ because it is easy, effective,  economical and ecofriendly and is belived to be a step toward green chemistry. In view of these observations and in continuation of our work on biologically active chalcones and their heterocycles [20], we have been planned to synthesize the new 1,4-bis(3-phenyl-4,5-dihydroisoxazol-5-yl)benzene derivatives from chalconesand also studied their antibacterial activity against esherishia coli and staphelococcas aureas .

    Performance of a local electron density trigger to select extensive air showers at sea level

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    Time coincident voltage pulses in the two closely space (1.6m) plastic scintillators were recorded. Most of the recorded events are expeted to be due to electrons in cosmic ray showers whose core fall at some distance from the detectors. This result is confirmed from a measurement of the frequency distribution of the recorded density ratios of the two scintillators

    An Integrated Subharmonic Coupled-Oscillator Scheme for a 60-GHz Phased-Array Transmitter

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    This paper describes the design of an integrated coupled-oscillator array in SiGe for millimeter-wave applications. The design focuses on a scalable radio architecture where multiple dies are tiled to form larger arrays. A 2 × 2 oscillator array for a 60-GHz transmitter is fabricated with integrated power amplifiers and on-chip antennas. To lock between multiple dies, an injection-locking scheme appropriate for wire-bond interconnects is described. The 2 × 2 array demonstrates a 200–MHz locking range and 1 × 4 array formed by two adjacent chips has a 60-MHz locking range. The phase noise of the coupled oscillators is below 100 dBc/Hz at a 1-MHz offset when locked to an external reference. To the best of the authors’ knowledge, this is the highest frequency demonstration of coupled oscillators fabricated in a conventional silicon integrated-circuit process

    Quality of life after cesarean and vaginal delivery

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    Objective: Cesarean rates in recent decades have been increasing and a number of studies have shown that cesarean increases maternal morbidities. The aim of this study is to compare the quality of life after cesarean and vaginal delivery. Methods: This prospective study was carried out on 356 pregnant women visiting urban health centers in Shahroud City, Northeast Iran, in 2011. The subjects completed the quality of life questionnaire in the third trimester of pregnancy and at 8 weeks postpartum. Results: In primiparas, the mean global QOL scores for the cesarean and vaginal delivery groups were 67.65±12.7 and 72.12±11.8, respectively. Also, the scores for the physical, psychological and social domains of QOL as well as the global score of QOL were higher in the vaginal delivery group than the cesarean group (p<0.05). In the case of primiparas, multiple regression analysis revealed that after adjusting for education, desirability of pregnancy and the General Health Questionnaire score, the delivery type remained as a predictor of the scores for the physical (R2=1.7%; B=-3.826; p=0.031; CI [-7.301, -.350]) and social (R2=2.5%; B=-5.708; p=0.017; CI [-10.392, -1.023]) domains of QOL and the global QOL score (R2=2.6%; B=-4.065; p=0.006; CI [-6.964, -1.164]). While multiparas, there was no relationship between QOL and type of delivery. Conclusion: In this sample of low-risk women, cesarean negatively affected the QOL of primiparas. More studies with larger sample sizes should be conducted to examine the effects of cesarean on QOL in both primiparas and multiparas within a shorter period after delivery. © OMSB, 2013

    The potency of commonly used disinfectants on bacteria isolated from in-animate surfaces in the microbiology laboratory, Umaru Musa Yardua university Katsina

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    Disinfection is the process of removing microorganisms including potentially pathogenic ones from the surface of in-animate objects. The ubiquity of microorganisms has implicated door knobs, human hands, desks surfaces etc. to be reservoirs of microorganisms. This study analyses three (3) samples from five (5) inanimate surfaces of the Microbiology laboratory, three different organisms were isolated and identified using series of biochemical tests, phenol coefficient and surface disinfection test were also carried out. The phenol coefficient test involve exposure of the isolates to different dilution of test disinfectants to determine the highest dilution factor that inhibit microbial growth while surface disinfection test involved the use of soiled slides to test the potency of the test disinfectants on the isolates. The organisms isolated were Staphylococcus aureus, Klebsiella sp. and E. coli. Klebsiella sp. showed the highest resistance to the test disinfectants than E. coli and S. aureus. The result of this study confirms the contamination of inanimate surfaces with variety of pathogenic bacteria (S. aureus 25%, E. coli 23% and Klebsiella sp. 52%). Disinfectant A had the highest phenol coefficient of 6.0, C had 4.0 and disinfectant B had the lowest phenol coefficient of 3.0. Microorganisms live as transient contaminants in fomites where they constitute a major health hazards as sources of community acquired infections. Therefore, constant and regular disinfection should always be conducted at different concentrations so as to determine the potent concentration against the adhered microorganisms on various surfaces of the laboratory.Keywords: Disinfection, Phenol coefficient, Surface disinfection, Contamination, Inanimate surfaces

    Synthesis, Characterization and Antibacterial Activity of Some New 5,5'-diphenyl-4,4',5,5'-tetrahydro-1H,1'H-3,3'-bipyrazole Derivatives

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    An efficient and practical synthesis of five compounds of pyrazoline derivatives structures was achieved through cyclization of hydrazine hydrate with 1,6-diphenylhexa-1,5-diene-3,4-dione using glacial acetic acid as catalyst under thermal conditions. These compounds have been characterized by FT-IR, elemental analysis (C.H.N.) and 1H NMR spectroscopy. Keywords:pyrazoline, chalcone, heterocycli

    The Association of Prothrombin Gene Mutations and Cytomegalovirus Infection with Abortion Among Iraqi Women

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    يُصنف الإجهاض على أنه إنهاء الحمل الناجم عن فشل أو إزالة الجنين من الرحم قبل إتمام الحمل. هناك عوامل مختلفة ترتبط بالإجهاض منها الكائنات الحية الدقيقة والعوامل الوراثية. ان الفيروس المضخم للخلايا هو أحد مسببات العدوى الفيروسية الخلقية التي تصيب مجموعة واسعة من الأشخاص. يعتبر جين البروثرومبين (معرف الجين: 14061 في NCBI) أحد الأسباب الأساسية التي تؤدي إلى تخثر الدم ووظيفة الإجهاض، وبالتالي فإن الهدف من الدراسة هو اكتشاف وربط الفيروس المضخم للخلايا وطفرة جين البروثرومبين بالإجهاض من خلال الأساليب الجينية والمناعية.  تم جمع 5 مل من حجم الدم الكامل من خلال وخز الوريد وتم تقسيمها إلى أنبوبتين، أحداهما تحتوي على EDTA والأخرى دون (أنبوب عادي) من 74 امرأة لديهن تاريخ إجهاض كمجموعة مريضات و74 امرأة بدون سجل إجهاض مع واحد على الأقل من الخصوبة الناجحة كمجموعة تحكم. تُستخدم PCRs الخاصة بأليل لتضخيم مناطق الجينات باستخدام بادئات جينية تحتوي على تعدد أشكال جينات البروثرومبين.أظهرت النتائج الحالية أن أكبر خطر للإجهاض لوحظ في النساء المصابات بتفاعلية مصلية IgG في 65 امرأة مع تردد (87.8٪) وكان أقل معدل للإجهاض في إيجابية مصلية IgM في 3 نساء بمعدل تكرار (4.1٪) و6 (8.1٪).) كانت إيجابية لـ IgM-وIgG يشير إلى امتلاكهم عدوى قديمة وحديثة. علاوة على ذلك، تُستخدم PCRs الخاصة بالأليل لتضخيم تعدد الأشكال البروثرومبين G20201A. أظهرت نتيجة هذه الدراسة عدم وجود علاقة بين تكرار مستوى النمط الجيني للبروثرومبين والإجهاض في النساء المصابات بفيروس CMV. في حين أن هناك علاقة ارتباط ذات دلالة إحصائية بين مجموعات الأليلات A وG والإجهاض في النساء المصابات بفيروس CMV.Abortion is categorized as the termination of conception caused by the failure or removal of the embryo from the uterus before the conclusion of pregnancy. Microorganisms and genetic factors are two of the many factors associated with abortion. Cytomegalovirus is a widespread congenital virus infection pathogen that affects a wide variety of people. The prothrombin gene is one of the essential causes that trigger blood clotting and the function of abortion women, therefore the aim of the study is to detect and associate Cytomegalovirus and prothrombin gene mutation (Gene ID: 14061 in NCBI) with abortion through genetic and immunological methods. Five ml of whole blood was collected from an intravenous puncture and divided into two tubes, one with EDTA and one without (plain tube) from 74 women with an abortion history as a patient group and 74 women without an abortion record who had at least one successful fertility as a control group. Allele-specific PCRs are used to amplify gene regions with genetic primers containing prothrombin gene polymorphisms. Current results have shown the greatest risk of abortion was observed in women patients with IgG seropositivity in 65 women with frequency (87.8%) and the lowest rate of abortion was in IgM seropositivity in 3 women with frequency (4.1%) and 6 (8.1%) were positive for IgM-and IgG indicating they have both an old and recent infections. Furthermore, allele-specific PCRs are used to amplify prothrombin G20201A polymorphism. The result of this study demonstrated there is no association between prothrombin genotype level frequency and abortion in CMV-infected women. While, there is a highly significant association between A and G Alleles combinations and abortion in CMV-infected women

    Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options

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    Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis. Assessment of serological and inflammatory markers of infection may be useful adjuncts in identifying those patients who are at a higher risk of developing vascular events, and in whom more aggressive treatments might be warranted
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